Denshichi Torimonocho: The Curse of the Silver Snake.

Kofu duty guard Yamauchi Hinata-kami cultivated illegal drugs and had them sold through Omiya, a drug wholesaler in Edo Muromachi. One day, a strange spell descends on Omiya, killing his wife Osetsu, and then his second daughter Okyo as well. After that, there was a rumor that a ghost playing a flute appeared in the town of Edo. Sanshiro Tachibana, a member of the Kitamachi Magistrate Doshin, asked Denshichi to investigate these incident.