It's a Man's World.

It's a Man's World is an American comedy-drama television series which aired on NBC from September 17, 1962, to January 28, 1963. Wes and Tom-Tom are friends going to college and with musician Vern share a houseboat. Wes also watches out for his younger brother Howie and the four of them deal with girls, jobs, and school. Occasionally the boys get serious but more often they use humor to handle situations.