Renseijutsushi Colette no H na Sakusei Monogatari.

Colette lives quietly with her master Priscilla in the mountains of a certain country, is learning alchemy, an epoch-making technology that synthesizes items using the semen of living things. Despite being still half-baked with no experience, Colette is able to become a full-fledged alchemist thanks to Priscilla's somewhat aggressive guidance. Now with her own studio, Colette works hard, but, while on a certain quest, she is prevented from accomplishing it by a powerful monster.