The Last Exit.

Darren and Jodi are in the middle-of-nowhere Maine on their way to a funeral. The reason they never make it is simple: werewolves. As other wayward travelers end up in their own battles for life, a suspected killer with a werewolf-sized chip on his shoulder is hunting the beast. It takes a couple of kids, some drunken hunters, and an urbanite from California to confront the legend and decide who or what is responsible for the carnage.